Dr Holly Roy
Profiles

Dr Holly Roy

Clinical Lectureship in Neurosurgery

Peninsula Medical School (Faculty of Health)

Biography

Biography

Academic clinical fellow in neurosurgery

Qualifications

BA, BM.BCh, MRCS, DPhil

Research

Research

Research interests

As a medical student I became interested in the role of neural oscillations in normal and pathological brain function. In order to pursue this interest I undertook an academic foundation job followed by DPhil in the Oxford Functional Neurosurgery under the supervision of Prof. Alexander Green. I also spent time at FMRIB (now WIN), supervised by Dr. Ricarda Menke. I used techniques including intracranial local field potential recording, diffusion weighted MRI and functional MRI to study the neural control of autonomic nervous system activity, with a focus on the neural control of the urinary bladder.

Since moving to Plymouth, I joined Prof. David Parkinson's group in order to gain experience of working with surgical animal models. I am currently working within the wider Brain Tumour Research Centre of Excellence to understand the role of Hippo signalling in ependymoma tumour development. Alongside this I have ongoing interests in continence and have been involved in the British Neurosurgical Trainee Research Collaborative project "Understanding Cauda Equina Syndrome", the International Continence Society neuro-urology working group and undertaking further work with my DPhil data. I am also collaborating with the Oral Microbiome Research Group on a project related to brain abscess development.

Publications

Publications

Key publications

Key publications are highlighted

Journals
Articles
Hoeritzauer I, Paterson M, Jamjoom AAB, Srikandarajah N, Soleiman H, Poon MTC, Copley PC, Graves C, MacKay S & Duong C (2023) 'Cauda equina syndrome' The Bone & Joint Journal 105-B, (9) 1007-1012 ,
Woodfield J, Hoeritzauer I, Jamjoom AAB, Lammy S, Pronin S, Hannan CJ, Watts A, Hughes L, Moon RDC & Roy H (2023) 'More questions than answers to the diagnosis and management of cauda equina syndrome—Authors’ reply' The Lancet Regional Health - Europe 27, 100606-100606 ,
Woodfield J, Hoeritzauer I, Jamjoom AAB, Jung J, Lammy S, Pronin S, Hannan CJ, Watts A, Hughes L & Moon RDC (2022) 'Presentation, management, and outcomes of cauda equina syndrome up to one year after surgery, using clinician and participant reporting: a multi-centre prospective cohort study' The Lancet Regional Health - Europe 24, 100545-100545 ,
Roy H, Bescos R, McColl E, Rehman U, Cray E, Belfield LA, Nweze K-D, Tsang K, Singleton W & Whitfield P (2022) 'Oral microbes and the formation of cerebral abscesses: a single-centre retrospective study' Journal of Dentistry ,
Roy HA, Smith MD, Blaber H, Fry CH, Pereira EA & Drake MJ (2022) 'Hypothesis: Disrupted Regulation of the Intracranial Vascular and Cerebrospinal Fluid Circulations Causes Nocturia' European Urology Focus 8, (1) 60-65 ,
Roy HA, Cascini N, Ajay B, Mukherjee S, McGavin L, Inman A, Wilkinson R & Whitfield PC (2021) 'Intracranial tuberculoma and the challenges of global neurosurgery' Advances in Clinical Neuroscience & Rehabilitation 20, (4) 26-28 ,
Roy HA, Nettleton J, Blain C, Dalton C, Farhan B, Fernandes A, Georgopoulos P, Klepsch S, Lavelle J & Martinelli E (2020) 'Assessment of patients with lower urinary tract symptoms where an undiagnosed neurological disease is suspected: A report from an International Continence Society consensus working group' Neurourology and Urodynamics 39, (8) 2535-2543 ,
Mukherjee SK, Arman DM, Roy HA, Khan RK, Afreen S, Hossain MA, Md Ziauddin -, Ekramullah SM, Rahman MM & Yusuf MA (2020) 'Status of ToRCH positivity among the children presented with congenital Hydrocephalus' Bangladesh Journal of Neurosurgery 9, (2) 121-125 ,
Roy H & Aziz T (2020) 'Indications and approaches for functional neurosurgery in multiple sclerosis, including the role for lesional surgery and deep brain stimulation' Medical Research Archives 8, (6) ,
Hyam JA, Roy HA, Huang Y, Martin S, Wang S, Rippey J, Coyne TJ, Stewart I, Kerr G & Silburn P (2019) 'Cardiovascular autonomic responses in patients with Parkinson disease to pedunculopontine deep brain stimulation' Clinical Autonomic Research 29, (6) 615-624 ,
Roy HA, Aziz TZ & Green AL (2019) 'Sensory thalamus and periaqueductal grey area local field potential signals during bladder filling' Journal of Clinical Neuroscience 68, 342-343 ,
Roy HA & Green AL (2019) 'The Central Autonomic Network and Regulation of Bladder Function' Frontiers in Neuroscience 13, ,
Hyam JA, Wang S, Roy H, Moosavi SH, Martin SC, Brittain JS, Coyne T, Silburn P, Aziz TZ & Green AL (2019) 'The pedunculopontine region and breathing in Parkinson's disease' Annals of Clinical and Translational Neurology 6, (5) 837-847 ,
Roy HA, Griffiths DJ, Aziz TZ, Green AL & Menke RAL (2019) 'Investigation of urinary storage symptoms in Parkinson's disease utilizing structural MRI techniques' Neurourology and Urodynamics 38, (4) 1168-1175 ,
Green AL, Debrah E, Roy HA, Rebelo P & Moosavi SH (2019) 'Letter to the editor: Thalamic deep brain stimulation may relieve breathlessness in COPD' Brain Stimulation 12, (3) 827-828 ,
Woodfield J, Hoeritzauer I, Jamjoom AAB, Pronin S, Srikandarajah N, Poon M, Roy H, Demetriades AK, Sell P & Eames N (2018) 'Understanding cauda equina syndrome: protocol for a UK multicentre prospective observational cohort study' BMJ Open 8, (12) e025230-e025230 ,
Roy H, Offiah I & Dua A (2018) 'Neuromodulation for Pelvic and Urogenital Pain' Brain Sciences 8, (10) 180-180 ,
Roy HA, Aziz TZ, Fitzgerald JJ & Green AL (2018) 'Beta oscillations and urinary voiding in Parkinson disease' Neurology 90, (17) e1530-e1534 ,
Roy H & Richards P (2017) 'The management of traumatic brain injury' Paediatrics and Child Health 27, (9) 395-400 ,
Roy HA, Pond D, Roy C, Forrow B, Foltynie T, Zrinzo L, Akram H, Aziz TZ, FitzGerald JJ & Green AL (2017) 'Effects of pedunculopontine nucleus stimulation on human bladder function' Neurourology and Urodynamics 37, (2) 726-734 ,
Roy HA, Green AL & Aziz TZ (2017) 'State of the Art: Novel Applications for Deep Brain Stimulation' Neuromodulation: Technology at the Neural Interface 21, (2) 126-134 ,
Roy HA & Magdum S (2014) 'Sub-aponeurotic fluid collection in a neonate associated with fetal scalp electrode monitoring: a brief communication' European Journal of Obstetrics & Gynecology and Reproductive Biology 181, 343-344 ,
Roy HA & Aziz TZ (2014) 'Deep brain stimulation and multiple sclerosis: Therapeutic applications' Multiple Sclerosis and Related Disorders 3, (4) 431-439 ,
Chapters
Roy HA & Green AL (2023) 'The bladder as a readout in neuroscience research' Neuro-Urology Research Elsevier 81-101 ,
Conference Papers
Cray E, Roy H, Lau S, Hannan A, Beard A, Noad R, Muquit S & Jeffery S (2022) 'Utility of neuropsychological tests in assessing response to cerebrospinal fluid drainage in idiopathic normal pressure hydrocephalus'
Presentations and posters
Parkinson DB, Laraba L, Roy H, Whitehouse J, Gregario SM & Dun X-P Parkinson DB, Laraba L, Roy H, Whitehouse J, Gregario SM & Dun X-P 'Hippo signalling in peripheral nerve development, repair and tumourigenesis' ,